Berlin JA, Colditz GA. A meta-analysis of physical activity in the prevention of coronary heart disease. Am J Epidemiol. 1990; 132:612-628.

Chiuve SE, McCullough ML, Sacks FM, Rimm EB. Healthy lifestyle factors in the primary prevention of coronary heart disease among men: benefits among users and nonusers of lipid-lowering and antihypertensive medications. Circulation. 2006; 114:160-167.

Eaton CB. Relation of physical activity and cardiovascular fitness to coronary heart disease, Part I: A meta-analysis of the independent relation of physical activity and coronary heart disease. J Am Board Fam Pract. 1992; 5:31-42.

Hu G, Jousilahti P, Borodulin K, Barengo NC, Lakka TA, Nissinen A, Tuomilehto J. Occupational, commuting and leisure-time physical activity in relation to coronary heart disease among middle-aged Finnish men and women. Atherosclerosis. 2007; 194:490-497.

Lee IM, Rexrode KM, Cook NR, Manson JE, Buring JE. Physical activity and coronary heart disease in women: is “no pain, no gain” passe? Jama. 2001; 285:1447-1454.

Lloyd-Jones D, Adams RJ, Brown TM, et al. Heart Disease and Stroke Statistics–2010 Update: A Report From the American Heart Association. Circulation. 2010; 121:e46-215.

Manson JE, Greenland P, LaCroix AZ, Stefanick ML, Mouton CP, Oberman A, Perri MG, Sheps DS, Pettinger MB, Siscovick DS. Walking compared with vigorous exercise for the prevention of cardiovascular events in women. N Engl J Med. 2002; 347:716-725.

Manson JE, Hu FB, Rich-Edwards JW, Colditz GA, Stampfer MJ, Willett WC, Speizer FE, Hennekens CH. A prospective study of walking as compared with vigorous exercise in the prevention of coronary heart disease in women. N Engl J Med. 1999; 341:650-658.

Oguma Y, Shinoda-Tagawa T. Physical activity decreases cardiovascular disease risk in women: Review and meta-analysis. American Journal of Preventive Medicine. 2004; 26:407-418.

Pate RP, Pratt M, Blair SN, Haskell WL, Macera CA, Bouchard C, Buchner D, Ettinger W, Heath GW, King AC, Kriska A, Leon AS, Marcus BH, Morris J, Paffenbarger, RS Jr., Patrick K, Pollock ML, Rippe JM, Sallis J, Wilmore JH. A recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine. JAMA. 1995; 273:402-7.

Sattelmair J, Pertman J, Ding EL, Kohl HW 3rd, Haskell W, Lee IM. Dose-response between physical activity and risk of coronary heart disease: a meta-analysis. Circulation. 2011 Aug 16;124(7):789-95.

Sesso HD, Paffenbarger R.S, Jr., Lee IM. Physical activity and coronary heart disease in men: The Harvard Alumni Health Study. Circulation. 2000;102(9):975-980.

Sofi F, Capalbo A, Cesari F, Abbate R, Gensini GF. Physical activity during leisure time and primary prevention of coronary heart disease: an updated meta-analysis of cohort studies. Eur J Cardiovasc Prev Rehabil. 2008; 15:247-257.

Weinstein AR, Sesso HD, Lee IM, Rexrode KM, Cook NR, Manson JE, Buring JE, Gaziano JM. The joint effects of physical activity and body mass index on coronary heart disease risk in women. Archives of Internal Medicine. 2008;168(8):884-890.

Williams PT. Physical fitness and activity as separate heart disease risk factors: a meta-analysis. Med Sci Sports Exerc. 2001; 33:754-761.

Yu S, Yarnell JW, Sweetnam PM, Murray L. What level of physical activity protects against premature cardiovascular death? The Caerphilly study. Heart. 2003;89(5):502 506.

Weller I, Corey P. The Impact of Excluding Non-Leisure Energy Expenditure on the Relation between Physical Activity and Mortality in Women. Epidemiology. 1998;9(6):632-635.


Abbot, R., et al. (2004). “Walking and dementia in physically capable elderly men ” JAMA 292: 1447-53.

Aberg MA, Pedersen NL, Toren K, et al. Cardiovascular fitness is associated with cognition in young adulthood. PNAS. 2009;106(49):20906-20911.

Buck, Sarah M., Charles H. Hillman, and Darla M. Castelli. 2008. The relation of aerobic fitness to Stroop Task performance in preadolescent children. Medicine & Science in Sports & Exercise 40:166–72.

Carlson, Susan A., Janet E. Fulton, Sarah M. Lee, Michele Maynard, David R. Brown, Harold W. Kohl, III, and William H. Dietz. 2008. Physical education and academic achievement in elementary school: Data from the early childhood longitudinal study. American Journal of Public Health 98:721–27.

Castelli, Darla M., Charles H. Hillman, Sarah M. Buck, and Heather E. Erwin. 2007. Physical fitness and academic achievement in third- and fifth-grade students. Journal of Sport and Exercise Psychology 29:239–52.

Coe, Dawn P., James M. Pivarnik, Christopher J. Womack, Mathew J. Reeves, and Robert M. Malina. 2006. Effect of physical education and activity levels on academic achievement in children. Medicine & Science in Sports & Exercise 38:1515–19.

Davis CL, Tomporowski PD, Boyle CA, et al. Effects of aerobic exercise on overweight children’s cognitive functioning: a randomized controlled trial. Res Q Exerc Sport. 2007 Dec;78(5):510-9.

Dik, M., Deeg, DJH, et al. (2003). “Early life physical activity and cognition at an older age.” J Clin Exp Neuropsychol 25: 643-53.

Dishman, Rod K., Kenneth J. Renner, Jill E. White-Welkley, K. A. Burke, Bradford N. Bunnell. 2000. Treadmill exercise training augments brain norepinephrine response to familiar and novel stress. Brain Research Bulletin 52:337–42.

Heyn, P., Abreu, BC, et al. (2004 ). “The effects of exercise training on elderly persons with cognitive impairment and dementia: a meta-analysis.” Arch Phys Med Rehabil 85: 1694-704.

Hillman, Charles H., Darla Castelli, Sarah M. Buck. 2005. Aerobic fitness and neurocognitive function in healthy preadolescent children. Medicine & Science in Sports & Exercise 37:1967–74.

Hillman, Charles H., Kirk I. Erickson, and Arthur F. Kramer. 2008. Be smart, exercise your heart: Exercise affects on brain and cognition. Nature Reviews Neuroscience 9:58–64.

Hillman Charles H., Robert W. Motl, Matthew B. Pontifex, Danielle Posthuma, Janine H. Stubbe, Dorret L. Boomsma, and Eco J. C. de Geus. 2006. Physical activity and cognitive function in a cross-section of younger and older community-dwelling individuals. Health Psychology 25:678–87.

Hu FB, Stampfer MJ, Colditz GA, Ascherio A, Rexrode KM, Willett WC, Manson JE. Physical activity and risk of stroke in women. JAMA. 2000;283:2961-2967

Kramer, Arthur F., Stanley J. Colcombe, Louis Bherer, Willie Dong, and William T. Greenough. 2004. Environmental influences on cognitive and brain plasticity during ageing. Journal of Gerontology: Medical Sciences 59A:940–57.

Mattson, M., Maudsley, S, Martin, B. BDNF and 5HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders. Trends in Neuroscience. 2004;27(10): 589-94.

Mattson MP. Hormesis Defined. Ageing Res Rev. 2008;7(1):1-7.

Mora, Francisco, Gregorio Segovia, and Alberto del Arco. 2007. Ageing, plasticity, and environmental enrichment: Structural changes and neurotransmitter dynamics in several areas of the brain. Brain Research Reviews 55:78–88.

Nybo L, Secher NH. Cerebral perturbations provoked by prolonged exercise. Progress in Neurobiology. 2004;72(4):223-261.

Panksepp, Jaak, Jeff Burgdorf, Cortney Turner, and Nakia Gordon. 2003. Modelling ADHD-type arousal with unilateral frontal cortex damage in rats and beneficial effects of play therapy. Brain and Cognition 52:97–105.

Panksepp, Jaak. 2007. Can PLAY diminish ADHD and facilitate the construction of the social brain? Journal of the Canadian Academy of Child and Adolescent Psychiatry 16:57–66.

Panksepp, Jaak. 2008. Play, ADHD, and the construction of the social brain: Should the first class each day be recess? American Journal of Play 1:55–79.

Pontifex MB, Hillman CH, Fernhall B, et al. The effect of acute aerobic and resistance exercise on working memory. Med Sci Sports Exerc. 2009;41(4):927-34.

Ratey, John J., and Eric Hagerman. 2007. Spark: The revolutionary new science of exercise and the brain.

Rovio, S., et al. 2005. Leisure-time PA at midlife and the risk of dementia and Alzheimer’s disease. Lancet Neurol 4: 705-711.

Sallis, James, Thomas L. McKensie, Bohdan Kolody, Michael Lewis, Simon J. Marshall, and Paul Rosengard. 1999. Effects of health-related physical education on academic achievement: Project SPARK. Research Quarterly for Exercise and Sport 70:127–34.

Sattelmair J & Ratey J. Physically active play and cognition: An academic matter? American Journal of Play. Winter 2009

Sattelmair JR, Kurth T, Buring JE, Lee IM. Physical activity and risk of stroke in women. Stroke. 2010 Jun;41(6):1243-50. Epub 2010 Apr 6.

Sibley, Benjamin A., and Jennifer L. Etnier. 2003. The relationship between physical activity and cognition in children: A meta-analysis. Pediatric Exercise Science 15:243–56.

Sigfusdottir, Inga D., Alfgeir Kristjansson, and John P. Allegrante. 2007. Health behaviour and academic achievement in Icelandic school children. Health Education Research 22:70–80.

Taras, Howard. 2005. Physical activity and student performance at school. Journal of School Health 75:214–18.

Tomporowski, P. (2003). “Effects of acute bouts of exercise on cognition.” Acta Psychol (almost) 112: 297-324.

van Praag, H., Gage, FH, et al. 2005. Running enhances neurogenesis, learning, and long-term potentiation in mice. Proceedings of the National Academy of Science 96: 13427-13431.

Vaynman, Shoshanna, Zhe Ying, and Fernando Gomez-Pinilla. 2004. Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. European Journal of Neuroscience 20:2580–90.

Vaynman S, Gomez-Pinilla F. Revenge of the “sit”: how lifestyle impacts neuronal and cognitive health through molecular systems that interface energy metabolism with neuronal plasticity. J Neurosci Res 2006;84(4):699-715.

Wendel-Vos GCW, Schuit AJ, Feskens EJM, Boshuizen HC, Verschuren WMM, Saris WHM, Kromhout D. Physical activity and stroke. A meta-analysis of observational data. Int J Epidemiol. 2004;33:787-798

Weuve J, Kang JH, Manson JE, Breteler MM, Ware JH, Grodstein F. Physical activity, including walking, and cognitive function in older women. JAMA. 2004 Sep 22;292(12):1454-61.

Willey JZ, Moon YP, Paik MC, Boden-Albala B, Sacco RL, Elkind MSV. Physical activity and risk of ischemic stroke in the northern manhattan study. Neurology. 2009;73:1774-1779

Williams PT. Reduction in incident stroke risk with vigorous physical activity: Evidence from 7.7-year follow-up of the national runners’ health study. Stroke. 2009;40:1921-1923


Booth FW, Chakravarthy MV, Gordon SE, Spangenburg EE. Waging war on physical inactivity: using modern molecular ammunition against an ancient enemy. J Appl Physiol. 2002; 93: 3–30.

Booth FW, Chakravarthy MV. Cost and Consequences of Sedentary Living: New Battleground for an Old Enemy. President’s Council on Physical Fitness and Sports: Research Digest. 2002;3(16).

Hamilton MT, Hamilton DG, Zderic TW. Role of Low Energy Expenditure and Sitting in Obesity, Metabolic Syndrome, Type 2 Diabetes, and Cardiovascular Disease. Diabetes November 2007;56(11):2655-2667

Chakravarthy M & Booth F. Eating, exercise, and “thrifty” genotypes: connecting the dots toward an evolutionary understanding of modern chronic diseases. J Appl Physiol. 2004; 96: 3-10.

Physical Activity Guidelines Advisory Committee. Physical Activity Guidelines Advisory Committee Report, 2008. Washington, DC 2008.

Sattelmair JR, Pertman JH, Forman DE. Effects of physical activity on cardiovascular and noncardiovascular outcomes in older adults. Clin Geriatr Med. 2009 Nov;25(4):677-702, viii-ix. Review.

US Department of Health and Human Services. Physical Activity Guidelines for Americans. Office of Disease Prevention and Health Promotion. 2008; October ( Publication No. U0036).

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